Subcellular location of PKCalphaII-GFP (green) in Green Monkey COS-7 cells using laser scanning confocal microscopy two days after transfection. The actin cytoskeleton is stained with Texas Red-phalloidin and the endoplasmic reticulum (purple) identified with an antibody to calreticulin.   By Lorene Langeberg, Scott Lab Manager at the Howard Hughes Medical Institute, Portland, OR.
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Diet and cardiovascular health: Chylomicron remnants and their emerging roles in vascular dysfunction in atherogenesis

The Royal Veterinary College, Camden, London, UK

18 - 19 December 2006

A Biochemical Society Focused Meeting

Proceedings (invited speakers) will be published in Biochemical Society Transactions

Abstract submission deadline: 9 October 2006
Abstract submission is now open.

Early registration deadline: 18 November 2006

Student travel grants are available for this meeting.


Scientific Programme

Organizers
Kathleen Botham (The Royal Veterinary College, UK)
Caroline Wheeler-Jones (The Royal Veterinary College, UK)
Sponsors
Biochemical Society Transactions
Portland Press
Royal Veterinary College

Timetable

Monday 18 December 2006 Tuesday 19 December 2006
14:15-17:25
Chylomicron remnants and cardiovascular disease
08:45-11:00
Chylomicron remnants and endothelial dysfunction
11:30-13:10
Chylomicron remnants and macrophage function
14:30-16:10
Chylomicron remnants and obesity, diabetes and the metabolic syndrome

Chylomicron remnants and cardiovascular disease

Monday 18 December 2006

11:00-14:00 Registration
14:00-14:15 Welcome from Chairman and from the Principal of the Royal Veterinary College
14:15-15:15 John Mamo (Curtin University of Technology, Australia)
Title to be confirmed
15:15-15:45 Coffee/tea break
15:45-16:20 Allen Cooper (Stanford University, USA)
Chylomicron remnants and atherosclerosis
16:20-16:55 Tom Sanders (King's College London, UK)
Post-prandial lipoproteins and thrombosis
16:55-17:10 Selected oral communication
17:10-17:25 Selected oral communication
17:30-19:00 Drinks reception and poster session

Chylomicron remnants and endothelial dysfunction

Tuesday 19 December 2006

8:45-9:20 Caroline Wheeler-Jones (Royal Vetenary College, UK)
Signalling mechanisms in the modulation of endothelial function by chylomicron remnants
9:20-9:55 Manuel Castro Cabezas (Sint Franciscus Gasthuis, The Netherlands)
Inflammation, endothelial function and postprandial lipemia
9:55-10:30 Valentina Ruiz Gutierrez (Consejo Superior de Investigaciones Científicas, Spain)
Modulation of the effects of chylomicron remnants on endothelial function by minor dietary lipid components
10:30-10:45 Selected oral communication
10:45-11:00 Selected oral communication
11:00-11:30 Coffee/tea break

Chylomicron remnants and macrophage function

Tuesday 19 December 2006

11:30-12:05 Kathleen Botham (The Royal Veterinary College, UK)
The induction of macrophage foam cells by chylomicron remnants
12:05-12:40 Elena Bravo (Istituto Superiore di Sanit? Italy)
Mechanisms involved in chylomicron remnant lipid uptake by macrophages
12:40-12:55 Charlotte Lawson (Royal Veterinary College, London, UK)
Chylomicron remnants and monocyte activation
12:55-13:10 Selected oral communication
13:10-14:30 Lunch and poster session

Chylomicron remnants and obesity, diabetes and the metabolic syndrome

Tuesday 19 December 2006

14:30-15:05 Fredrik Karpe (University of Oxford, UK)
Chylomicron, chylomicron remnant and VLDL metabolism in the metabolic syndrome
15:05-15:40 Spencer Proctor (University of Alberta, Canada)
Chylomicron and apoB 48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome
15:40-15:55 Selected oral communication
15:55-16:10 Selected oral communication

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